Making Cannabis Oil Suppositories
With Pamela Javid Haymes
This is great for upping your dosage. When necessary we can get onto one gram a day using this method in the period of two weeks.
You can end up with 2 grams a day and not get very high at all.
Suppository drug delivery is becoming a more viable option for pharmacists and nurses, since suppositories provide direct access to the systemic circulation, efficiently bypassing the portal circulation and the liver metabolism on the first pass. It is a little known fact that the lower and middle hemorrhoidal veins bypass the liver and do not undergo first-pass metabolism. Therefore, suppositories can deliver the drug rapidly to the lower and middle hemorrhoidal veins for absorption. The rectum is an interesting area for drug absorption because it is not buffered and has a neutral pH. It also has very little enzymatic activity, thus enzymatic degradation does not occur. The rectal mucosa is more capable than the gastric mucosa of tolerating various drug-related irritations. This is especially important in patients with gastric disease. The anorectal physiology provides a large surface area for drug absorption.
Cocoa butter stays firm at room temperature and does'nt irritate the delicate mucous membranes of the wall of the rectum.
Thick straw [ Kentucky Krusher straw works well ]
Lighter /Washingpeg / paperclip
Makes about 7 suppositories
Close one end of straw with lighter,paperclip or washingpeg to seal
Check how much fits into straw by shortly filling with water ,pouring into syringe to measure [eg 14mil [making suppositories of 2cm each]
Melt cocoa butter [melts luke warm 24degreesCel] in a tot glass by putting the glass in a cup of hot water.
Suck up melted cocoa-butter [eg14ml] with syringe,close tip[with finger] and pull out plunger
[at opposite end] then add desired dosage drops [eg suppositories with 5 drops each need a total of 35drops], put back plunger and shake
Place upright in freezer for 12hours then can be kept in cabinet or fridge [normally dont melt at room temperature]
Cut into 2cm portions/suppositories then can be kept in cabinet or fridge . Cocoa butter stays firm at room temps and doesn't irritate the delicate mucous membranes of the anus
added 35 drops and want dosage of 5 drops each
Cut into 7 portions,giving suppositories of 5 drops each